InitialCancerChemotherapy

The Gist

Chemotherapy – What Is It?

Chemotherapy is a treatment that uses drugs to destroy or stop the growth of cancer cells, usually administered intravenously. Since cancer cells grow and divide faster than healthy cells, most anticancer drugs are designed to destroy rapidly growing cells. However, there are also healthy cells that multiply more quickly, so chemotherapy also affects these cells. This is what usually causes side effects. The rapidly growing healthy cells affected by chemotherapy include blood cells formed in the bone marrow, cells of the digestive tract, as well as those of the reproductive system (genital organs) and hair (affecting hair follicles), which is why hair falls out and head coverings are used after chemotherapy. Do not be alarmed—we will definitely discuss how to minimize unwanted effects and improve your well-being.

The chemotherapy treatment process and drug administration
Chemotherapy – the effect of drugs on cancer cells

How long does a chemotherapy course last?

The duration of a chemotherapy course varies, depending on the type and stage of cancer, the patient's condition, the drugs administered, and their dosage. Before starting treatment, your doctor will discuss the planned course of treatment with you; be sure to ask if you are not informed. Three weeks is called a treatment cycle, and several cycles make up a chemotherapy course, which can last from 3 to 6 months.

Possible side effects of chemotherapy

How long do the side effects of chemotherapy last?

Cells should gradually recover after chemotherapy, so side effects should gradually decrease. However, chemotherapy can also cause long-term changes, affecting your quality of life, so it is essential to take care of your body's recovery, because, unfortunately, the rehabilitation system is somewhat creaky…

Some people avoid serious long-term effects of chemotherapy, but this is not a coincidence! You yourself must remain responsible for your own health. Admit it, modern medicine does not engage in prevention. Modern medicine treats symptoms and consequences (and does it well), but does nothing to ensure you never return to the hospital… and that you stay healthy!

If you have already been diagnosed with cancer – you will not avoid chemotherapy, radiotherapy, and other modern treatments, and you certainly should not avoid them, because you are already too late for prevention. However, now you can and must take control and no longer entrust your health to anyone. You will have to take it upon yourself to be among the percentage of people who successfully overcome cancer, recover, and experience no side effects. You can truly do this. We will now discuss how to shift the statistics in your favor.

Body recovery after chemotherapy

To be effective, cancer drugs and treatments are aggressive, so the body's immune, digestive, and other systems are left in a difficult state after chemotherapy. As mentioned, the modern medical system for prevention and rehabilitation after chemotherapy is failing, and you will have to fill this gap yourself. You will need to restore your immune system and supply your body with vitamins, minerals, fiber, antioxidants, immune-boosting, and other substances so that your body has the resources to manage and heal.

The human body tends to heal and manage itself, but you must help it.

You need to identify and eliminate what is unhealthy, feeds cancer, and pollutes the body. First of all – processed carbohydrates and all sugar-containing products – this is cancer food [1]. You need to avoid sugar, pastries, juices, sodas, cakes, loaves, buns, chocolates, alcohol, candies, semi-finished products… Any product containing sugar: glucose, sucrose, dextrose, fructose, galactose, maltose… and any other "-ose". Yes, all these names are sugar. Besides the fact that sugar causes addiction no less than some heavily banned substances [2], it causes inflammation [3], and it feeds cells that have become cancerous. Do you agree that it would be logical to avoid excess sugar in the body?

Nutrition during cancer

It is recommended to restore vitamins, minerals, and bacterial balance through proper nutrition; then you will not need countless supplements. When you obtain necessary substances naturally from food, the body absorbs them maximally. Moreover, the absorption of synthetic supplements in the body is still debated, so choose only natural supplements. And when you obtain necessary substances naturally from food, the body absorbs them maximally.

It is recommended to eat sauerkraut daily. It may seem funny, but sauerkraut contains a very wide range of minerals and vitamins. During fermentation, not only do the nutrients in cabbage increase, but their bioavailability also improves. Sauerkraut is also a source of probiotics – it improves digestion and promotes the growth of healthy intestinal flora. In the October 23, 2002 issue of the Journal of Agriculture and Food Chemistry , Finnish scientists reported that isothiocyanates produced during sauerkraut fermentation inhibit the growth of cancer cells.

Nutrition during cancer - healthy foods
Healthy nutrition is an important part of body recovery during treatment

It has been proven [4]that Omega 3 helps preserve muscle mass and function in cancer patients even during active treatment. Also, during chemotherapy, omega-3 fatty acids can contribute to a reduced inflammatory response. You can take supplements or eat plenty of fatty fish such as herring, mackerel, or tench.

Your best friend must become vegetables, and as many raw, unprocessed ones as possible, because you need to fill up with life – good bacteria, enzymes, fiber, probiotics, vitamins, minerals. No processed foods, only pure food. No calorie restriction, eat as much as you want and as many good (unheated) fats as possible. Make sure these products are definitely in your diet: mushrooms, nuts, berries (not jam), seeds (sunflower seeds, flaxseeds), avocado, fish. [5]Due to daily rushing and convenience, we have unconsciously started eating processed foods and drinking inferior beverages, yet real food is so delicious and there are so many recipes. It is advisable to limit only 'simple' carbohydrates. Complex carbohydrates [6] – these are sugar molecules joined into more complex chains, found in plants, often accompanied by fiber, so they do not raise blood sugar levels and are absorbed more slowly and healthily. Such real food does not need to be limited: whole grains, buckwheat, oats, nuts, potatoes, etc. Legumes are especially recommended: peas, beans, lentils, mung beans, asparagus, chickpeas, and particularly black beans, because promising studies have emerged [7] showing they contribute to DNA maintenance [8].

How to Maximally Restore the Body

The best example is probably Japan. The healthcare system strives to combine the achievements of modern medicine with treatment practices refined over centuries. This is also the case with cancer. Extracts derived from Shiitake mushrooms are prescribed for oncology. These active substances are administered before, during, and after chemotherapy. As it should be, because numerous studies have been conducted to clarify the effects of active substances extracted from Shiitake.

The 'pioneer' in this field can be considered Dr. Kisaku Mori, who founded the 'Institute of Mushroom Research' in Tokyo in 1936 (Institute of Mushroom Research). One of the first experiments was conducted on mice: mice suffering from sarcoma were treated with small doses of Shiitake extract. In 6 out of 10 mice, the tumor completely regressed. Increasing the concentration achieved 100% efficacy – the tumor regressed in all mice. The study revealing Shiitake's anti-tumor properties sparked enormous interest and a wave of subsequent research. Soon Hamuro and Chihara confirmed obtaining the same results. Thus, the first researchers, including Mori, Ikekawa, Hamuro, Chihara, Maeda, Taguchi, Nanba, Aoki and many others have indisputably proven that certain active compounds of mushrooms result in:

Anticancer mushroom substances

Dr. Chihara was the first to isolate the compound Lentinan from Shiitake (lat. Lentinus edodes). This polysaccharide exhibits antibacterial, antimicrobial, antiviral, anticancer, and immune-stimulating properties. It can also protect chromosomes from damage caused by anticancer drugs. This was observed in experiments with mice in Japan: when treated with this polysaccharide before chemotherapy, the white blood cell count did not decrease at all.

Medicinal mushrooms alongside chemotherapy
Medicinal mushrooms – scientifically confirmed immunomodulatory effects

How Lentinan improves chemotherapy outcomes

There is not just one active compound, and many of them have various mechanisms of anticancer activity. Undoubtedly, the most important of these is the stimulation and strengthening of the immune system, which initiates immunobiological changes. Although it sounds simple, these are quite complex processes – these compounds, also called bio-modulators, influence the complex functioning of the immune system, acting both generallyand directly cancer cells. One such bio-modulator is Lentinan, derived from the Shiitake mushroom. Lentinan binds to the surface of lymphocytes, activating macrophages, T-helper cells, and NK cells (natural killer cells – Natural Killer (NK) cells)). All of this increases antibody production, including interleukins (IL-2 and others) and interferon (IFN-g). Then the "attack" on altered cells begins. The activity and interaction of these cells is what we call the immune system.

What human studies have been conducted?

There are quite a few human studies on the anticancer effects of medicinal mushrooms, including strictly controlled clinical trials. Unlike cancer cell studies in laboratories or (impressive result) studies in animals, one cannot recklessly conduct experiments on humans for obvious ethical reasons... Therefore, most of the studies already conducted were carried out alongside conventional cancer treatment (chemotherapy). In these studies, the result was always the same: the anticancer substances of medicinal mushrooms are effective when used together with surgical treatment, chemotherapy, radiotherapy, and the results are much better than with conventional/standard cancer treatment alone [9]. Due to these results, such cancer treatment, combining medicinal mushroom extract with "standard" treatment, is common practice, most widespread in China and Japan. Dr. Taguchi conducted studies with 275 cancer patients. They used Lentinan together with chemotherapy for 3 months. Results:

Isoda N, Eguchi Y, Nukaya H, et al. Clinical efficacy of superfine dispersed lentinan (beta-1,3-glucan) in patients with hepatocellular carcinoma. Hepatogastroenterology. 2009 Mar-Apr;56(90):437-41.
Oba K, Kobayashi M, Matsui T, Kodera Y, Sakamoto J. Individual patient based meta-analysis of lentinan for unresectable/recurrent gastric cancer. Anticancer Res. 2009 Jul;29(7):2739-45.
Hazama S, Watanabe S, Ohashi M, et al. Efficacy of orally administered superfine dispersed lentinan (beta-1,3-glucan) for the treatment of advanced colorectal cancer. Anticancer Res. 2009 Jul;29(7):2611-7.
Shimizu K, Watanabe S, Watanabe S, et al. Efficacy of oral administered superfine dispersed lentinan for advanced pancreatic cancer. Hepatogastroenterology. 2009 Jan-Feb;56(89):240-4.
Okuno K, Uno K. Efficacy of orally administered Lentinula edodes mycelia extract for advanced gastrointestinal cancer patients undergoing cancer chemotherapy: a pilot study. Asian Pac J Cancer Prev. 2011;12(7):1671-4.
Israilides C, Kletsas D, Arapoglou D, et al. In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes. Phytomedicine. 2008.
Sullivan R, Smith JE, Rowan NJ. Medicinal mushrooms and cancer therapy: translating a traditional practice into Western medicine. Perspect Biol Med. 2006;49(2):159-170.
Boon H, Wong J. Botanical medicine and cancer: a review of the safety and efficacy. Expert Opin Pharmacother. 2004;5(12):2485-2501.
Yeung KS, Gubili J. Shiitake Mushroom (Lentinula edodes). J Soc Integr Oncol. 2008;6(3):134-135.

Immune system support

Chemotherapy suppresses the immune system, so it requires active support. Lentinan AXT from Zenius Labs™ is a concentrated formula of polysaccharide extracts from several mushrooms, designed to strengthen the immune system during oncological diseases.

More about Lentinan AXT →

What else to take? Antioxidants

Antioxidants. One of the main causes of adverse reactions to chemotherapy, especially drugs targeting DNA, is an increased number of reactive oxygen species (oxidants). Numerous studies have been and are being conducted to reduce the number of these free radicals.

A common question has been whether antioxidants taken alongside chemotherapy diminish its effect, as they might appear to counteract each other, but in the human body, it is not so simple. After studying the effect of antioxidant use during and after chemotherapy and comparing 93 clinical trials, [10] it turned out that in 70% of cases, chemotherapy effectiveness increases, in 88% of cases, antioxidant use reduces toxicity, and in 63% of cases, survival time is prolonged.

Quite a number of substances have antioxidant properties, but not all of them are equally potent. Perhaps the most well-known antioxidant is vitamin C, but it is not the strongest. Here are several popular antioxidants, ranked from strongest compared to vitamin C:

Antioxidant Potency (compared to vit. C)
Astaxanthin 6000 times stronger
Vitamin E 12 times stronger
Coenzyme Q10 7.5 times stronger
Resveratrol 2 times stronger

The use of antioxidants in cancer is indisputable. Make sure that along with Lentinan you get astaxanthin.

DNA protection and antioxidant effect

Lentinan AXT from Zenius Labs™ combines in one formula not only the most potent mushroom polysaccharide extracts but also the maximum dose of astaxanthin. It is one of the most powerful known antioxidants, protecting cellular DNA from oxidative stress. One formula – comprehensive support.

More about Lentinan AXT →

What you need to know before buying Lentinan

Only water-based polysaccharide extracts are used. There are also ethanol (alcohol)-based extracts; this extraction method is cheaper and faster, therefore it does not yield the substances we need. Carefully read the supplement composition.

Extract amount and strength. The higher the polysaccharide content (as a percentage), the more mushrooms were needed during production to extract the active substance from the mushroom… It can be 5%, 15%, 30% (very rarely more). Naturally, 30% is 6 times more effective than 5%. The polysaccharide content must also be stated on the packaging.

Daily extract amount. The minimum recommended daily amount of 30% extract is 1200mg.

How and how much to take supplements after chemotherapy?

Where to buy the best Lentinan supplements?

To achieve results, it is very important to use the highest quality, potent, and reliable products. You can purchase the recommended Lentinan at the Zenius Labs™ store.

Frequently asked questions

What is chemotherapy and how does it work?

Chemotherapy is a treatment using drugs that destroy rapidly dividing cells in the body. It affects not only cancer cells but also some healthy ones, thus causing side effects. The goal of treatment is to stop or slow down tumor growth.

Can immunity be supported during chemotherapy?

Yes, and it is very important. Chemotherapy strongly suppresses the immune system, making the body vulnerable. Concentrated mushroom polysaccharide extracts can help activate NK cells and macrophages. It is important to choose a concentrated multi-extract formula such as Lentinan AXT from Zenius Labs™.

How long does a chemotherapy course last?

A chemotherapy course typically lasts from 3 to 6 months, but may be longer. Treatment occurs in cycles – drug administration is followed by a rest period during which the body recovers.

What are the most common side effects of chemotherapy?

The most common are fatigue, nausea, hair loss, loss of appetite, mouth sores, and increased susceptibility to infections. Side effects are usually temporary and subside after the treatment course is completed.

How to speed up recovery after chemotherapy?

The most important factors are proper nutrition (high-quality animal fats – eggs, butter, wild fish, duck – which support hormone production and prevent weight loss during chemotherapy), adequate rest, physical activity, and immune system support. Concentrated mushroom polysaccharide formulas combined with astaxanthin can help protect cell DNA and accelerate recovery.

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